Had COVID - 19 symptoms in the last 2 days? Apply here to help us make testing accessible to all.
back to all FAQs

How have you validated the accuracy of your tests?

To date we have conducted three clinical studies. The first was a UK Government-supported National Institute for Health Research (NIHR) study across ten UK hospitals; the second was with Liverpool School of Tropical Medicine, and the third is a community study that we have led ourselves. We have also carried out our own analytical assessments, as well as two Public Health England analytical assessments.

We have worked with over 300 negative patient samples and around 100 COVID-19 positive patients across our studies. We are also currently carrying out a 650+ patient clinical trial with sites in the UK, USA and Brazil to provide us with a higher volume of clinical data, and with a view to additional regulatory approvals to widen the reach of the impact we can have globally in pandemic recovery.

What is a lateral flow test?

A lateral flow test is a simple diagnostic device designed to detect the presence or absence of a target substance in a liquid sample without the need for specialised and costly equipment.

The most commonly recognised type of lateral flow rapid test strip is the pregnancy test.

When did you start?

Vatic was founded in October 2019 by Alex Sheppard and Dr. Mona Kab Omir.

When the first wave of COVID-19 started in the UK in early 2020, our team immediately saw an opportunity to contribute to global efforts to tackle the pandemic, and leveraged work already underway on antigen testing to quickly start developing the KnowNowᵀᴹ Test.

How is a KnowNowᵀᴹ Test administered?

There are just 4 simple steps to the KnowNowᵀᴹ Test.

  1. Swab the mouth: The KnowNowᵀᴹ Test requires just a saliva sample to be taken easily and comfortably from the mouth. We know how uncomfortable and painful other lateral flow antigen tests or polymerase chain reaction (PCR) tests can be, with swabs going high into nostrils and all the way back to tonsils. It was really important to us that people would feel happy to take a KnowNow test on a regular basis.
  2. Shake the tube: The saliva swab is placed into a buffer solution in a small tube, and shaken up to mix it well.
  3. Squeeze on panel: A few drops of the mixed solution is squeezed onto the KnowNowᵀᴹ Test device.
  4. Know in 15 minutes: It takes just 15 minutes for the positive or negative result to appear in the test result window on the KnowNowᵀᴹ Test device. No need to wait 24-48 hours for results, as you would with a PCR test.

How does KnowNowᵀᴹ compare to COVID-19 PCR tests?

KnowNowᵀᴹ offers two key benefits over polymerase chain reaction (PCR) tests.

The first benefit is that the KnowNowᵀᴹ test needs only a saliva sample, which can be taken easily and comfortably from the mouth. PCR tests usually need a nasopharyngeal, anterior nasal or tonsil sample, all of which are painful and unpleasant for the individual being tested and more challenging to collect effectively for the clinical professional administering the test. No one wants to be made to cry or gag, or make someone else cry or gag, on a regular basis!

The second benefit is that the KnowNow test uses its unique detection mechanism to determine whether an individual is actually infectious, whereas PCR tests identify whether SARS-CoV-2 viral matter is present in an individual's body, regardless of whether it is already inactive.

Although PCR tests have been seen as the "gold standard" test for the SARS-CoV-2 virus, they do have a number of drawbacks. Laboratory processing is required, meaning that there is a delay before results can be returned, and the associated costs are relatively high. Also the detection mechanism does not specifically identify whether individuals are infectious. In fact, PCR tests detect the virus long after the infectious period, and individuals can continue to test positive for a mean of 17 days after they have stopped being able to infect others (source). This means that people who are not infectious are unnecessarily quarantined as a result of a positive PCR test.

How much space do I need to store the tests?

One box contains 25 tests, and measures 20cm (L) x 21cm (W) x 8cm (H).

The space required depends on how many tests you require at any given time. However, as the KnowNowᵀᴹ Tests can be stored at any temperature between 2 and 30 degrees, special storage facilities should not be required in the UK, unless there is unusually hot weather.

How frequently should employees or visitors be tested?

We recommend that individuals are tested as regularly as possible to keep workplaces, venues and communities safe.

It is important to remember that individuals can still go on to be exposed to the virus following a negative test result. Additionally, a high proportion of infectious people show no symptoms at all, and so regular testing is key to breaking the chain of transmission.

Depending on the scenario, we would recommend that testing is performed every 2-3 days, or daily, depending on the scenario.

Why test people who don't have symptoms?

SARS-CoV-2 is able to spread from individuals who are pre-symptomatic or asymptomatic. As a result, testing and isolation based on symptoms alone will not be sufficient to stop the spread.

This narrative review of 16 clinical studies around the globe concludes that between 40-45% of those infected with SARS-CoV-2 never develop symptoms, and that these asymptomatic carriers can infect others for an extended period, perhaps longer than 14 days.

Regular community testing with a rapid antigen test like the KnowNowᵀᴹ Test to identify asymptomatic, but infectious, individuals offers one way to break the chain of transmission and enable the re-opening of societies.

Where do you make your KnowNowᵀᴹ tests?

KnowNowᵀᴹ Tests have been invented, developed and manufactured in the UK.

What is SARS-CoV-2?

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the name given by the International Committee on Taxonomy of Viruses (ICTV) to the virus responsible for causing the disease, COVID-19.

What's the long term vision for Vatic beyond COVID-19?

We’re focused on developing our predictive health technology and tests so that we can make medicine more proactive and help to predict illness before it becomes acute or infectious. We want to empower people to feel in charge of their own health and wellbeing by making testing more readily accessible and available, allowing for earlier prediction and prevention of acute illnesses.

Had COVID - 19 symptoms in the last 2 days? Apply here to help us make testing accessible to all.